Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple sclerosis in American blacks

M A Morariu, M Linden

    Acta Neurologica Scandinavica
    |September 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Multiple sclerosis (MS) disproportionately affects Black individuals, with geographic origin influencing disease onset, diagnosis, and progression. Environmental factors and genetics may play a role in MS risk and clinical course among Black Americans.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Highly tunable cryogenic resonance circuit for radio frequency magnetic field generation using in situ switch-bank tuning.

    The Review of scientific instruments·2025
    Same author

    Elephants, bushes, hot porridge… and clinical intuition?

    Nordic journal of psychiatry·2023
    Same author

    Inhibitor-assisted synthesis of silica-core microbeads with pepsin-imprinted nanoshells.

    Journal of materials chemistry. B·2020
    Same author

    Genetic selection for bovine chromosome 18 haplotypes associated with divergent somatic cell score affects postpartum reproductive and metabolic performance.

    Journal of dairy science·2019
    Same author

    A fast sol-gel synthesis leading to highly crystalline birnessites under non-hydrothermal conditions.

    Dalton transactions (Cambridge, England : 2003)·2017
    Same author

    The effects of perceived USB-delay for sensor and embedded system development.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2017
    Same journal

    Editorial.

    Acta neurologica Scandinavica·2022
    Same journal

    Advances in sudden unexpected death in epilepsy.

    Acta neurologica Scandinavica·2022
    Same journal

    Non-convulsive seizures and non-convulsive status epilepticus in neuro-intensive care unit.

    Acta neurologica Scandinavica·2022
    Same journal

    Positron emission tomography in autoimmune encephalitis: Clinical implications and future directions.

    Acta neurologica Scandinavica·2022
    Same journal

    Seizure detection based on wearable devices: A review of device, mechanism, and algorithm.

    Acta neurologica Scandinavica·2022
    Same journal

    Walking confidence and perceived locomotion ability explain participation after stroke: A cross-sectional experimental study.

    Acta neurologica Scandinavica·2022
    See all related articles

    Area of Science:

    • Neurology
    • Epidemiology
    • Genetics

    Background:

    • Multiple sclerosis (MS) is a chronic neurological disease.
    • Black individuals are underrepresented in MS patient populations.
    • Geographic factors and migration patterns may influence MS risk.

    Purpose of the Study:

    • To investigate the prevalence and clinical characteristics of multiple sclerosis (MS) in Black patients.
    • To compare MS onset, diagnosis, and disease course between Northern-born and Southern-born Black individuals.
    • To explore potential genetic and environmental factors contributing to MS in Black Americans.

    Main Methods:

    • Retrospective study of 312 MS patients diagnosed between 1968-1977 at Henry Ford Hospital.
    • Analysis of demographic data, including race and geographic origin (Northern-born vs. Southern-born).

    Related Experiment Videos

  • Comparison of clinical characteristics, age of onset, age of diagnosis, and disease course between patient groups.

    • Main Results:

    • Black patients constituted 17% of the MS population, despite comprising 50% of the general hospital population.
    • No significant differences in clinical characteristics or death rates were observed between White and Black MS patients.
    • Southern-born Black patients exhibited a later age of onset and diagnosis, and a higher prevalence of chronic progressive MS compared to Northern-born Black patients.

    Conclusions:

    • Geographic origin and migration history are associated with differences in MS presentation among Black Americans.
    • Environmental exposures, potentially linked to geographic location, may influence MS risk, onset, and progression in Black individuals.
    • A combination of genetic predisposition and environmental factors likely contributes to the development and clinical course of MS in the Black population.