Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Increased mechanical muscle irritability syndrome

R Alberca, E Rafel, J M Castilla

    Acta Neurologica Scandinavica
    |October 1, 1980
    PubMed
    Summary

    This study details a patient with a unique neuromuscular syndrome and cerebellar atrophy. Muscle abnormalities were observed, distinct from known muscle diseases, and independent of the cerebellar disorder.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [In Memoriam. Allen D. Roses (1943-2016)].

    Revista de neurologia·2017
    Same author

    Acute stroke trials: Reasons for patient withdrawal.

    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2015
    Same author

    [Neurological catastrophes due to medical errors].

    Neurologia (Barcelona, Spain)·2010
    Same author

    Internal carotid artery stenting in patients with near occlusion: 30-day and long-term outcome.

    AJNR. American journal of neuroradiology·2010
    Same author

    Volume and composition of emboli in neuroprotected stenting of the carotid artery.

    AJNR. American journal of neuroradiology·2008
    Same author

    [Apolipoprotein E4 in dementia with Lewy bodies].

    Neurologia (Barcelona, Spain)·2008

    Area of Science:

    • Neurology
    • Muscle Physiology
    • Histopathology

    Background:

    • Presents a case study of a patient with complex neurological symptoms.
    • Highlights the diagnostic challenges in rare neuromuscular and cerebellar disorders.

    Observation:

    • Electrically silent muscle movements, myoedema, and myotonia-like responses to mechanical stimulation were observed.
    • Patient exhibited a cerebellar syndrome, characterized by cerebellar atrophy.
    • Neuromuscular and cerebellar symptoms appeared semeiologically independent.

    Findings:

    • Muscle contractions indicated a myofibrillar apparatus dysfunction.
    • Histochemical and electron microscopy revealed morphological muscle abnormalities.
    • These abnormalities were not linked to any specific known muscle disease.

    Implications:

    • Suggests a novel neuromuscular disorder potentially involving myofibrillar apparatus.
    • Underscores the importance of comprehensive investigation in patients with concurrent neurological and neuromuscular deficits.
    • Contributes to the understanding of idiopathic cerebellar atrophies and associated neuromuscular conditions.

    Related Experiment Videos