Related Experiment Video
Updated: Jul 11, 2026

Imaging of Estrogen Receptor-α in Rat Pial Arterioles using a Digital Immunofluorescent Microscope
Published on: November 29, 2011
Production of blood capillary contracting substance after administration of estrogen to rabbit
Abstract:
Estradiol was continuously injected to female rabbits with a daily dose of 10,000 units for 50 days, and androgen was similarly given to male rabbits. Samples were obtained from livers of these rabbits according to the method of "placental capillary contracting substance", and their capillary contracting activities were determined. A substance showing a high activity was obtained from the liver of the rabbit treated with estradiol. A capillary contracting substance was also extracted from the urine of pregnant women, but it was hardly obtained from the urine of normal men.
Related Concept Videos
Regulation of Angiogenesis and Blood Supply
Vascular Spasm
Hormonal Regulation of Blood Pressure
Epinephrine and Norepinephrine
The adrenal medulla releases epinephrine and norepinephrine, catecholamines that enhance and extend the sympathetic or "fight or flight" physiological response. These hormones escalate heart rate and the force of contraction while...
Autoregulation of Blood Flow
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.

