Electroretinogram (ERG) and visual evoked response (VER) studies in patients with optic disc drusen

Non-corneal ERGs, recorded from infraorbital skin electrodes to flash stimulation and mid-occipital and parasagittal VERs to both flash stimulation and pattern reversal were performed in 26 patients with optic disc drusen. ERGs were normal in all patients. The mean VER amplitude was lower in the eyes with optic disc drusen than the mean amplitude of VERs in the normals but the interindividual variation was also so great in normals that the difference was not significant. The waveform of the major positive peak was quite often broad or split. VER latencies were usually in normal range although the visual field defects could be rather severe. Some other cause was present when the major positive peak was delayed.