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Case report. Clindamycin associated pseudomembranous colitis
Acta Paediatrica Scandinavica
|January 1, 1981
Abstract:
Pseudomembranous colitis is rare in children. We describe a case associated with clindamycin in which Clostridium difficile and its enterotoxin were isolated from the stool. Treatment with oral vancomycin brought about a prompt and complete recovery.
Insights
Pseudomembranous colitis is a rare condition in children. A case linked to clindamycin showed Clostridium difficile and its toxin, successfully treated with oral vancomycin.
Area of Science:
- Pediatric Gastroenterology
- Infectious Diseases
- Microbiology
Background:
- Pseudomembranous colitis is uncommon in pediatric populations.
- Antibiotic-associated colitis requires careful consideration in children presenting with severe diarrhea.
Observation:
- A pediatric case of pseudomembranous colitis associated with clindamycin use is presented.
- Clostridium difficile and its associated enterotoxin were identified in stool samples.
Findings:
- The patient experienced a prompt and complete recovery following treatment with oral vancomycin.
- This case highlights the efficacy of oral vancomycin in managing Clostridium difficile-associated colitis in children.
Implications:
- Early recognition and appropriate antibiotic stewardship are crucial for managing pediatric Clostridium difficile infections.
- This case reinforces the importance of considering Clostridium difficile as a cause of colitis in children, even when rare.