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Case report. Clindamycin associated pseudomembranous colitis

J Beesley, E J Eastham, R H Jackson

Acta Paediatrica Scandinavica

|January 1, 1981

Summary

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Pseudomembranous colitis is a rare condition in children. A case linked to clindamycin showed Clostridium difficile and its toxin, successfully treated with oral vancomycin.

Area of Science:

Pediatric Gastroenterology
Infectious Diseases
Microbiology

Background:

Pseudomembranous colitis is uncommon in pediatric populations.
Antibiotic-associated colitis requires careful consideration in children presenting with severe diarrhea.

Observation:

A pediatric case of pseudomembranous colitis associated with clindamycin use is presented.
Clostridium difficile and its associated enterotoxin were identified in stool samples.

Findings:

The patient experienced a prompt and complete recovery following treatment with oral vancomycin.
This case highlights the efficacy of oral vancomycin in managing Clostridium difficile-associated colitis in children.

Implications:

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Early recognition and appropriate antibiotic stewardship are crucial for managing pediatric Clostridium difficile infections.

This case reinforces the importance of considering Clostridium difficile as a cause of colitis in children, even when rare.