Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Computerized interpretation of minimum inhibitory concentration antimicrobic susceptibility testing

R K Wertz, J E Swartzberg

    American Journal of Clinical Pathology
    |March 1, 1981
    PubMed
    Summary

    This study introduces a computerized system for interpreting minimum inhibitory concentration (MIC) values in antimicrobial susceptibility testing. The algorithm aids laboratories in understanding complex MIC data for better patient treatment decisions.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Infections associated with intra-spinal catheter-pump systems for severe pain management.

    The Journal of hospital infection·2002
    Same author

    CD-ROM. A new advance in medical information retrieval.

    JAMA·1986
    Same author

    Pathology-important advances in clinical medicine: assessing fetal lung maturity.

    The Western journal of medicine·1984
    Same author

    What every pathologist should know and be able to do in laboratory data processing and computers: relating to consultants.

    Pathologist·1982
    Same author

    What every pathologist should know and be able to do in laboratory data processing and computers: systems analysis and planning.

    Pathologist·1981
    Same author

    What pathologists should know and be able to do in laboratory data processing and computers: software.

    Pathologist·1981

    Area of Science:

    • Clinical Microbiology
    • Medical Informatics
    • Pharmacology

    Background:

    • Quantitative antimicrobial susceptibility testing using minimum inhibitory concentration (MIC) is increasingly common in US clinical laboratories.
    • Interpreting MIC values is complex and requires specialized laboratory services.
    • Existing methods for MIC interpretation can be challenging to implement consistently.

    Purpose of the Study:

    • To present a straightforward computerized algorithm for interpreting MIC values.
    • To provide a practical tool for laboratories to enhance antimicrobial susceptibility testing interpretation.
    • To document a system used successfully for over three years in clinical settings.

    Main Methods:

    • Development of a computer algorithm for MIC interpretation.

    Related Experiment Videos

  • Incorporation of semigraphic output to display relative susceptibility across dosages and body sites.
  • Inclusion of specific considerations like beta-lactamase production for Staphylococcus aureus and toxic aminoglycoside levels.

    • Main Results:

    • The algorithm provides a semigraphic output for clear visualization of susceptibility data.
    • It accounts for specific microbial and drug factors, enhancing interpretation accuracy.
    • A compendium of achievable antimicrobial levels with literature references is included.

    Conclusions:

    • The computerized scheme offers a simple and effective method for MIC interpretation in clinical laboratories.
    • This approach aids in managing complex antimicrobial susceptibility data.
    • The system supports informed therapeutic decisions by providing comprehensive and documented susceptibility information.