Orbital melanocytic hamartoma

Area of Science:

• Ophthalmology
• Dermatology
• Pediatric Oncology

Background:

• Melanocytic hamartomas are benign neoplasms composed of melanocytes.
• Orbital and ocular involvement by melanocytic hamartomas is uncommon.
• Neonate presentation requires careful evaluation due to potential for local invasion and malignant transformation.

Observation:

• A male Chinese neonate presented with a melanocytic hamartoma.
• The hamartoma extensively involved the entire orbit and the intraocular structures.
• The orbital bones and eyelid skin were unaffected.

Findings:

• The lesion was diagnosed as a melanocytic hamartoma.
• Histopathological examination confirmed the benign nature of the hamartoma.
• The extent of involvement highlighted the potential for significant orbital and ocular compromise.

Implications:

• Early diagnosis and monitoring are crucial for managing orbital melanocytic hamartomas in neonates.
• Understanding the potential for local invasion is vital for surgical planning and prognosis.
• Awareness of rare malignant transformation underscores the need for long-term follow-up.