Treatment of psoroptic mange with avermectins

Area of Science:

• Veterinary Parasitology
• Animal Health
• Dermatology

Background:

• Psoroptes cuniculi is a significant ectoparasite causing mange in rabbits.
• Effective and safe treatments are crucial for rabbit welfare and preventing economic losses.

Purpose of the Study:

• To evaluate the efficacy of various avermectin analogues against Psoroptes cuniculi in rabbits.
• To compare the effectiveness of topical versus subcutaneous administration routes.

Main Methods:

• Rabbits infested with Psoroptes cuniculi were treated with different avermectin analogues.
• Treatment administration included topical application and subcutaneous injection.
• The efficacy was assessed by monitoring mite populations and clinical signs.

Main Results:

• Good control of Psoroptes cuniculi infestations was achieved across tested avermectin analogues.
• Both topical and subcutaneous administration routes, particularly with 22,23-dihydroavermectin B1, proved effective.
• Significant reduction in mite burden and improvement in rabbit condition were observed.

Conclusions:

• Avermectin analogues, including 22,23-dihydroavermectin B1, are effective for controlling Psoroptes cuniculi in rabbits.
• Both topical and subcutaneous administration methods offer viable treatment options.
• These findings support the use of avermectins in managing rabbit mange.