Related Experiment Video
Updated: Feb 7, 2026

06:26
Particle Image Velocimetry Investigation of Hemodynamics via Aortic Phantom
Published on: February 25, 2022
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Summary
Penile erection in men does not require the closure of efferent veins from the corpora cavernosa. Studies show blood flows out of the corpora cavernosa during erection, disproving the venous closure theory.
Area of Science:
- Urology
- Physiology
Background:
- The prevailing theory suggested that closure of efferent veins from the corpora cavernosa is essential for human penile erection.
- This study investigated the necessity of venous closure for achieving penile erection.
Purpose of the Study:
- To determine if the closure of efferent veins from the corpora cavernosa is a prerequisite for human penile erection.
- To challenge the established theory regarding the mechanism of penile erection.
Main Methods:
- Direct infusion of 133Xe into the corpora cavernosa in 133 men.
- Performance of cavernosography in conjunction with sexual stimulation to induce erection.
- Monitoring 133Xe clearance curves and contrast medium flow to assess changes during erection.
Main Results:
- In flaccid penises, 133Xe clearance curves showed a gentle path, and contrast medium remained longer.
- During sexual stimulation-induced erection, 133Xe clearance curves fell rapidly, unlike the expected gentle course for venous closure.
- Contrast medium rapidly flowed out of the corpora cavernosa upon erection.
Conclusions:
- The human penis can achieve erection without the closure of the efferent vein from the corpora cavernosa.
- The findings indicate that venous closure is not essential for penile erection, challenging previous theories.

