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Related Experiment Videos

Reliability of lifetime diagnosis. A multicenter collaborative perspective

N C Andreasen, W M Grove, R W Shapiro

    Archives of General Psychiatry
    |April 1, 1981
    PubMed
    Summary
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    Lifetime diagnoses are reliably assessed in nonpatients using the Schedule for Affective Disorders and Schizophrenia-Lifetime Version. This finding is crucial for genetic and epidemiological studies utilizing such diagnostic data.

    Area of Science:

    • Psychiatry
    • Epidemiology
    • Genetics

    Background:

    • Lifetime diagnostic data are essential for various genetic, epidemiological, and nosological research.
    • Assessing the reliability of lifetime diagnoses in nonpatient populations is critical for study validity.

    Purpose of the Study:

    • To evaluate the reliability of lifetime psychiatric diagnoses in a nonpatient sample.
    • To determine if diagnoses made using the Schedule for Affective Disorders and Schizophrenia-Lifetime Version (SADS-L) and Research Diagnostic Criteria (RDC) are consistent over time.

    Main Methods:

    • Interviews were conducted with ill and well relatives of probands within the National Institute of Mental Health Collaborative Study of the Psychobiology of Depression.
    • Subjects underwent three interviews to assess both short-interval and long-interval test-retest reliability.

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    Main Results:

    • Short-interval test-retest reliability for diagnoses and symptoms was excellent.
    • Long-interval test-retest reliability also demonstrated high consistency.

    Conclusions:

    • Lifetime psychiatric diagnoses can be reliably established in nonpatient populations.
    • The SADS-L and RDC are dependable tools for obtaining reliable lifetime diagnostic information in research settings.