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Follicular psoriasis

L Stankler, S W Ewen

    The British Journal of Dermatology
    |February 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Follicular psoriasis presents in two distinct forms: a widespread adult type and plaque-like lesions in children. Histology reveals hair follicle involvement, suggesting it

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    Area of Science:

    • Dermatology
    • Pathology

    Background:

    • Psoriasis is a chronic inflammatory skin condition.
    • Follicular involvement in psoriasis is not well-characterized.

    Purpose of the Study:

    • To describe the clinical and histological features of follicular psoriasis.
    • To investigate the role of the hair follicle in psoriatic lesions.

    Main Methods:

    • Case report of ten patients with follicular psoriasis.
    • Clinical observation of lesion presentation in adults and children.
    • Histopathological examination of early and older psoriatic lesions.

    Main Results:

    • Two distinct clinical types identified: adult (widespread, thigh lesions) and pediatric (plaque-like, trunk lesions).

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  • Early lesions showed dermal infiltrate with prominent mast cells and normal hair follicles.
  • Older lesions exhibited nucleated cells in the hair follicle ostium.

    • Conclusions:

    • Follicular psoriasis presents with unique clinical and histological characteristics.
    • The hair follicle appears to be affected in psoriatic skin disease.
    • Further research is warranted to understand the pathogenesis of follicular psoriasis.