[Hyperkeratotic variant of Darier's disease. Successful oral treatment using an aromatic retinoid (Ro 10-9395)]

Oral aromatic retinoid (Ro 10-9359) in the treatment of a patient with hyperkeratotic Darier's disease yielded excellent results, which could be maintained over a period of 14 months by continuous administration of the drug. No serious side effects occurred which would have necessitated discontinuation of the therapy.