The ABO(H) paradoxical and aberrant secretion in human saliva

The paradoxical secretion and aberrant secretion of the ABH substances have been studied in the saliva of 251 and 283 subjects, respectively. A standardized hemagglutination-inhibition method was used and the results were scored by an Inhibition Index. Frequencies of 4.3% for paradoxical secretion and of 5.3% for aberrant secretion were observed. Gel chromatography on Sephadex G-25 showed that only the paradoxical secretors have in their saliva the oligosaccharides which inhibit nonspecifically the anti-A, anti-B and anti-H reagents.