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Intralesional corticosteroids

J P Callen

    Journal of the American Academy of Dermatology
    |February 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Intralesional corticosteroids offer an alternative to systemic treatments in dermatology. While generally safe, local side effects like skin atrophy can occur depending on preparation and application.

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    Area of Science:

    • Dermatology
    • Pharmacology

    Background:

    • Intralesional corticosteroids are frequently utilized in dermatology.
    • They serve as an adjunct to topical treatments or an alternative to systemic corticosteroids.

    Purpose of the Study:

    • To review the use of intralesional corticosteroids in clinical dermatology.
    • To discuss available preparations, administration methods, and adverse effects.

    Main Methods:

    • Review of literature on intralesional corticosteroid use.
    • Discussion of administration techniques (syringe/needle, Dermo-Jet).
    • Comparison of corticosteroid preparations, highlighting triamcinolones.

    Main Results:

    • Triamcinolone preparations offer favorable physical characteristics.

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  • Systemic absorption and adverse effects are minimal due to low dosages.
  • Local adverse effects, primarily skin atrophy, are dose and site-dependent.

    • Conclusions:

    • Intralesional corticosteroids are a valuable dermatological tool.
    • Careful consideration of preparation, dosage, and application site is crucial to minimize local adverse effects like atrophy.