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Related Experiment Videos

A multicenter study of ICU drug utilization

M L Farina, A Levati, G Tognoni

    Intensive Care Medicine
    |April 1, 1981
    PubMed
    Summary

    Drug utilization review in intensive care units identified key areas for therapeutic intervention, including antibiotic and cardiovascular drug use. Simple review techniques can improve hospital drug practices.

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    Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia·2013

    Area of Science:

    • Hospital Pharmacy
    • Clinical Pharmacology
    • Intensive Care Medicine

    Background:

    • Hospital practice requires regular evaluation to ensure optimal patient care.
    • Intensive care units (ICUs) present complex therapeutic challenges.
    • Drug utilization is a critical component of hospital quality assurance.

    Purpose of the Study:

    • To analyze medical records from 15 ICUs to identify areas needing intervention in drug therapy.
    • To assess the effectiveness of drug utilization review (DUR) techniques in improving therapeutic practices.

    Main Methods:

    • Analysis of medical records from 15 ICUs.
    • Inclusion of data on admission details, patient demographics, pharmacological history, length of stay, outcome, and diagnosis.
    • Focus on specific therapeutic areas: antibiotic therapy, steroid use for shock, hemostasis, and cardiovascular drugs.

    Main Results:

    • Identified specific needs for intervention in antibiotic therapy, steroid use for shock, hemostasis management, and cardiovascular drug administration.
    • Highlighted interhospital variations in diagnostic and care criteria, and documented inappropriate therapeutic practices.
    • Revealed a lack of reliable data registration, prompting discussions with clinicians.

    Conclusions:

    • Simple drug utilization review techniques are effective and inexpensive tools for improving hospital therapeutic practices.
    • Discussions with clinicians led to decisions on drug formulary exclusion, information programs, and controlled clinical trials.
    • Active intervention is specifically needed in areas such as antibiotic therapy and cardiovascular drug use within ICUs.

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