Infection and transmission studies with Plasmodium gonderi in the Macaca mulatta monkey

Eight different anophelines--Anopheles freeborni, An. maculatus, An. dirus, An. stephensi, An. atroparvus, An. sundaicus, An. quadrimaculatus, and An. albimanus--were shown to be susceptible to infection with a strain of Plasmodium gonderi from the drill. Mandrillus leucophaeus. Transmission was obtained via the bites of An. freeborni, An. maculatus, An. stephensi, and An. dirus mosquitoes to Macaca mulatta. Prepatent periods in Macaca mulatta monkeys following sporozoite inoculation ranged from 7 to 15 days with a median of 12.5 days. Relapses from fixed-tissue stages following treatment with chloroquine or quinine sulfate were not demonstrated.