Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Glass microelectrode tip capacitance: its measurement and a method for its reduction

M C Cornwall, M V Thomas

    Journal of Neuroscience Methods
    |February 1, 1981
    PubMed
    Summary

    Improving microelectrode performance for bioelectric signal measurement is crucial. Coating electrodes significantly reduces capacitance, enhancing amplifier frequency response for cellular studies.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Comparison of wet brewers' grains or dried distillers' grains as supplements to conserved bermudagrass forage as winter feeding options for beef cows.

    Journal of animal science·2017
    Same author

    Smoking-related cotinine levels and host responses in chronic periodontitis.

    Journal of periodontal research·2013
    Same author

    Expression of two nuclear genes encoding chloroplast proteins during early development of cucumber seedlings.

    Planta·2013
    Same author

    Bleaching of mouse rods: microspectrophotometry and suction-electrode recording.

    The Journal of physiology·2012
    Same author

    Bone remodeling-associated salivary biomarker MIP-1α distinguishes periodontal disease from health.

    Journal of periodontal research·2011
    Same author

    Smoking and periodontal disease: discrimination of antibody responses to pathogenic and commensal oral bacteria.

    Clinical and experimental immunology·2011

    Area of Science:

    • Biophysics
    • Electrophysiology
    • Cellular Neuroscience

    Background:

    • Input amplifiers for bioelectric signal measurement face limitations from microelectrode resistance and capacitance.
    • Existing capacitance neutralization techniques are incomplete due to finite amplifier bandwidth and electrode resistance effects.

    Purpose of the Study:

    • To present a method for measuring and predicting microelectrode distributed capacitance.
    • To describe a technique for reducing microelectrode capacitance to improve amplifier performance.

    Main Methods:

    • A novel coating technique was developed to reduce the capacitance per unit length of microelectrodes.
    • The method allows for prediction and measurement of distributed capacitance in microelectrodes.

    Related Experiment Videos

    Main Results:

    • Coating the microelectrode exterior near the tip reduced electrode capacitance per unit length by up to 7-fold.
    • This reduction significantly improves the frequency response of input amplifiers used in cellular measurements.

    Conclusions:

    • Minimizing electrode capacitance before neutralization is essential for optimal amplifier performance.
    • The described coating technique offers a practical solution for enhancing microelectrode performance in bioelectric signal acquisition.