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Predicting patients' warfarin requirements

P A Routledge, D M Davies, S M Bell

    Lancet (London, England)
    |October 22, 1977
    PubMed

    In 34 patients undergoing anticoagulant therapy with warfarin a close relationship has been observed between the logarithm of the 'Thrombotest' response to a loading dose (10 mg/day for three days) and the maintenance dose required to achieve an anticoagulant response of 8-12% (thrombo-test). This relationship appears to be close enough to enable maintenance dosages to be predicted.

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