[Peculiarities and difficulties in the systematic drug therapy of chronic schizophrenics (schizophrenic "defect")]

Difficulties are discussed that have occurred in the medicamentous treatment of chronic patients with a so-called schizophrenic defect. The main problem was that in case of a greater drive-increasing effect component of the drug (in the concrete case "Defecton") a recrudescence of productive-schizophrenic symptoms may occur in connection with the increase in drive. The authors' own opinion (Lange) with respect to a treatening "defect", psychopathological radical of the chronic schizophrenic residual condition ("defect"), personality-dependent syndrome structure with secondary symptoms, iaterogenisation and institutiogenisation of the "defect" ("institution artefact") is discussed.