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Updated: Aug 19, 2026

Murine Fetal Echocardiography
Published on: February 15, 2013
Insights
A poorly defined right heart border on infant chest X-rays often indicates an underlying issue. Computed tomography scans revealed pulmonary or pleural disease in most cases, highlighting the need for further investigation.
Area of Science:
- Pediatric Radiology
- Diagnostic Imaging
Background:
- The silhouette sign on plain chest radiographs can be challenging to interpret in infants.
- A poorly defined right heart border in infants is a common radiographic finding.
Purpose of the Study:
- To investigate the causes of a poorly defined right heart border in infants using computed tomography (CT).
- To elucidate the significance of the silhouette sign in pediatric thoracic imaging.
Main Methods:
- Computed tomographic (CT) scans of the lower thorax were performed on ten infants.
- Patients were selected based on plain chest radiographs showing poorly defined right heart borders.
Main Results:
- Satisfactory CT scans were obtained in eight of the ten infants.
- Pulmonary or pleural disease was identified in seven of the eight infants with interpretable CT scans.
- In one infant, thymic enlargement obscured the right heart border.
Conclusions:
- A poorly defined right heart border in infants under one year of age is frequently an abnormal finding.
- CT imaging is valuable for diagnosing the underlying causes of the silhouette sign in pediatric patients.
- Early identification of pulmonary or pleural abnormalities is crucial in infants presenting with this radiographic finding.
Abstract:
Computed tomographic scans of the lower thorax were obtained of ten infants whose plain chest radiographs showed poorly defined right heart borders. Satisfactory studies in eight of these children showed the explanation of the silhouette sign. Pulmonary or pleural disease was seen in seven of the eight. In one, the thymus obscured the heart border. A poorly defined right heart border in children in the first year of life is often abnormal.
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