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Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases
07:47

Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases

Published on: December 6, 2016

Clinical phenomena and their correlation to angiographic findings in cerebrovascular disease

D J Thurman, C H Millikan

    Stroke
    |January 1, 1981
    PubMed

    Insights

    Clinical symptoms suggest focal ischemic cerebrovascular disease, but cerebral angiography is essential. Angiography reveals arterial lesions in most patients, yet lesion characteristics like severity and morphology cannot be predicted clinically.

    Area of Science:

    • Neurology
    • Vascular Medicine
    • Radiology

    Background:

    • Focal ischemic cerebrovascular disease presents with clinical symptoms suggestive of arterial compromise.
    • Atherosclerosis is a common underlying cause of cerebrovascular disease.

    Purpose of the Study:

    • To evaluate the correlation between clinical presentation and angiographically confirmed arterial lesions in patients with suspected focal ischemic cerebrovascular disease.
    • To determine if clinical manifestations can predict the characteristics and extent of atherosclerotic lesions.

    Main Methods:

    • Cerebral angiography was performed on 71 patients presenting with clinical evidence of focal ischemic cerebrovascular disease.
    • Clinical data including symptoms and signs were analyzed.
    • Angiographic findings, including lesion distribution, morphology, and stenosis severity, were documented.

    Main Results:

    • Cerebral angiography identified an appropriate arterial lesion in 77% of the studied patients.
    • Clinical manifestations did not reliably predict the dissemination, morphology, or severity of atherosclerotic lesions.
    • While clinical assessment can suggest the presence of cerebrovascular disease, it cannot determine the specific nature or extent of lesions.

    Conclusions:

    • Cerebral angiography is crucial for accurately diagnosing and characterizing atherosclerotic cerebrovascular disease.
    • Clinical evaluation is insufficient for predicting the detailed characteristics of arterial lesions in the cerebrovasculature.
    • Further research may explore advanced imaging or biomarker techniques to complement clinical assessment.

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