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Mesenteric lymphadenitis due to Yersinia enterocolitica
Virchows Archiv. A, Pathological Anatomy and Histology
|January 1, 1981
Summary
Histopathology reveals specific changes in mesenteric lymph nodes due to Yersinia enterocolitica infections. These findings aid in diagnosing this bacterial infection in lymph node biopsies.
Area of Science:
- Pathology
- Microbiology
- Immunology
Background:
- Yersinia enterocolitica infections can affect mesenteric lymph nodes.
- Accurate histopathological diagnosis is crucial for patient management.
Purpose of the Study:
- To describe the specific histopathological features of Yersinia enterocolitica infection in mesenteric lymph nodes.
- To aid in the differential diagnosis of mesenteric lymphadenitis.
Main Methods:
- Analysis of biopsy material from 14 confirmed cases of Yersinia enterocolitica infection.
- Histopathological examination of mesenteric lymph nodes.
- Serological tests and fecal cultures for etiological confirmation.
Main Results:
- Mesenteric lymph nodes showed thickened capsules with edema and metachromatic staining.
- Hyperplasia of cortical and paracortical pulp with increased immunoblasts, plasmablasts, and plasma cells.
- Dilated sinuses filled with basophilic cells, including plasmacytoid cells and precursors.
Conclusions:
- Yersinia enterocolitica infection presents a distinct histological pattern in mesenteric lymph nodes.
- Histopathology can assist in differentiating Yersinia enterocolitica lymphadenitis from other causes.
- The findings contribute to the understanding of Yersinia enterocolitica pathogenesis in lymph nodes.