[Iatrogenic gynecomastia in aldosterone-antagonist therapy]

In casuistic form is reported on a patient with double-sided painful gynaecomasty and development of a node in the right breast under therapy with aldosterone antagonists. In this case the pathogenetic factors in the development of spironolactone-induced gynaecomasties are discussed. After a longer application of spironolactone must be reckoned with a gynaecomasty particularly when chronic liver diseases exist.