[Changes in the nervous system in lupus crises]

In 31 patients suffering from systemic lupus erythematosus, morphological examinations of the central and peripheral nervous system were carried out. In the nervous system, changes of the connective tissue, the vessels and the myelin membranes of the nervous fibres were discovered. Characteristic of the systemic lupus erythematosus were nuclear pathology and appearance of micronecroses in the cerebral tissue. The most pronounced changes in the nervous system were noted in 14 cases of autoimmune lupus crises. In these cases, the disease was distinguished for a high clinical and immunological activity.