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Ataxic hemiparesis from a midbrain mass

P E Bendheim, B O Berg

    Annals of Neurology
    |April 1, 1981
    PubMed
    Summary

    Ataxic hemiparesis syndrome in a child with leukemia was linked to a midbrain mass, challenging previous understandings of lesion location. This finding expands the known anatomical basis for this neurological syndrome.

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    Area of Science:

    • Neurology
    • Pediatric Oncology

    Background:

    • The ataxic hemiparesis syndrome is characterized by ipsilateral motor and cerebellar deficits.
    • Previous literature localized lesions causing this syndrome primarily to the basis pontis.

    Observation:

    • A 10-year-old boy with leukemia presented with ipsilateral corticospinal and cerebellar signs, indicative of ataxic hemiparesis.
    • Computed tomography identified a mass lesion in the contralateral rostral midbrain in this patient.

    Findings:

    • This case report challenges the established anatomical localization of the ataxic hemiparesis syndrome.
    • The findings suggest that the rostral midbrain is a potential site for lesions causing ataxic hemiparesis.

    Implications:

    • The anatomical substrate for ataxic hemiparesis may be broader than previously recognized, including the rostral midbrain.
    • This expands the differential diagnosis for neurological signs in pediatric patients with central nervous system lesions.

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