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Normothermic Ex Situ Heart Perfusion in Working Mode: Assessment of Cardiac Function and Metabolism
Published on: January 12, 2019
An appraisal of blood salvage techniques in vascular and cardiac operations
Insights
Blood salvage and reinfusion significantly reduces the need for homologous blood in cardiac surgery patients. This technique is safe, practical, and cost-effective for reducing transfusion requirements.
Area of Science:
- Cardiovascular Surgery
- Transfusion Medicine
Background:
- Cardiac surgery often necessitates blood transfusions.
- Homologous blood transfusions carry inherent risks.
Purpose of the Study:
- To compare the efficacy of intraoperative blood salvage and reinfusion versus traditional homologous blood use in cardiac operations.
- To evaluate the impact of blood salvage on transfusion requirements and patient outcomes.
Main Methods:
- Three patient groups were studied: Group 1 (homologous blood only), Group 2 (intraoperative and postoperative salvage), and Group 3 (intraoperative and continuous postoperative salvage).
- Transfusion volumes, hospital stays, blood chemistry, and costs were analyzed.
- Red blood cell (RBC) survival was assessed in Group 3.
Main Results:
- Patients undergoing blood salvage (Groups 2 and 3) required significantly less whole blood and packed RBCs compared to Group 1.
- Average reductions were approximately one-third for whole blood and one-fourth for packed RBCs.
- Hospital stays, blood chemistry, and costs remained comparable across all groups.
Conclusions:
- Intraoperative blood salvage and reinfusion is a safe and practical method for reducing homologous blood use in cardiac surgery.
- Available technology supports the effective implementation of blood salvage techniques.
- This approach offers substantial savings in blood product utilization without compromising patient outcomes or increasing costs.
Abstract:
This study compares blood salvage and reinfusion with the use of homologous blood in three groups of patients undergoing coronary artery bypass graft replacement or other cardiac operation. In Group 1 (100 patients), homologous blood was used and no effort was made to salvage blood. In Group 2 (68 patients), blood was salvaged before and after bypass and mediastinal blood was salvaged for 24 hours postoperatively. In Group 3 (46 patients), blood was salvaged before and after bypass and postoperatively. The average patient in Groups 2 and 3 required approximately one-third the amount of whole blood and approximately one-fourth the amount of packed red blood cells (RBC) required by a Group 1 patient. The hospital stays, blood chemistry levels, and costs per patient were comparable for the three groups. RBC survival studies in Group 3 patients showed a mild decrease from normal values. This study shows that currently available equipment and techniques allow safe and practical blood salvage during cardiac and vascular operations.
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