[In vitro activity of fosfomycin]

The in vitro activity of phosphomycin has been compared with other antibiotics in 1703 bacterial strains isolated from pathological specimens sent to the Laboratory from various divisions of the hospital. Results were first class on both gram-positive and gram-negative flora. It was in first place as regards staphylococcus (97.4% sensitive strains), citrobacter (68.6%), proteus mirabilis (73.1%), indole positive proteus (48.2%). It also predominated in pseudomonas (54.6%) and E. coli (86.7%). In view of the fact that gram-negative infections are taking on a predominant position within the hospital environment, it is considered that phosphomycin should be rightfully included among the antibacterial drugs in routine use.