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Photosensitivity to sulfisoxazole ointment
Archives of Ophthalmology (Chicago, Ill. : 1960)
|April 1, 1981
Summary
Sulfisoxazole diolamine can cause photosensitivity in patients with staphylococcal blepharitis. Applying the ointment at bedtime and covering eyelids during sun exposure can prevent this adverse drug reaction.
Area of Science:
- Ophthalmology
- Dermatology
- Pharmacology
Background:
- Staphylococcal blepharitis is a common eyelid infection often treated with topical sulfonamides.
- Sulfisoxazole diolamine is a sulfonamide antibiotic used in ophthalmic preparations.
- Drug-induced photosensitivity is a known, albeit uncommon, side effect of certain medications.
Observation:
- A 35-year-old male patient developed photosensitivity during treatment for staphylococcal blepharitis.
- The photosensitivity reaction occurred while using a sulfisoxazole diolamine ophthalmic ointment.
- The patient's symptoms were manageable with specific application timing and sun protection.
Findings:
- Topical sulfisoxazole diolamine can induce photosensitivity reactions.
- Photosensitivity reactions to this drug can be mitigated through careful administration and protective measures.
- The occurrence of photosensitivity should be considered in refractory or worsening cases of staphylococcal blepharitis.
Implications:
- Clinicians should be aware of the potential for photosensitivity with sulfisoxazole diolamine in blepharitis treatment.
- Patient education on sun exposure and application timing is crucial for managing this side effect.
- Considering drug-induced photosensitivity can aid in diagnosing and managing resistant eyelid infections.