Related Experiment Video
Updated: Aug 15, 2026

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
Published on: January 20, 2010
[Technic of muscle transplant for complete diaphragmatic aplasia (author's transl)]
Abstract:
The authors report a technic of muscular flap, to repair complete diaphragmatic aplasia. Based on a precise anatomical principle, they modified the Holcomb procedure (1961). The repair uses the Transversus abdominis muscle and the intercostal muscular layer. One case of survical with a satisfactory evolution can be attributed to the intervention. However, we must keep in mind that the prognosis is linked to the pulmonary hypoplasia associated with the malformation. As shown in the series we must emphasize that the degree of pulmonary involvement is not strictly related to the extend of the diaphragmatic effect.

