Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Familial polymorphous cold eruption

S Martin, J Eastern, J M Knox

    Cutis
    |February 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    A rare genetic condition causes a painful, red rash and fever after cold exposure. This familial polymorphous cold eruption is inherited in an autosomal dominant pattern.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The analysis of serum urate utilizing immobilized uricase.

    Applied biochemistry and biotechnology·2013
    Same author

    Memories, fantasies, archetypes: an exploration of some connections between cognitive science and analytical psychology.

    The Journal of analytical psychology·2001
    Same author

    Elevated levels of circulating adhesion molecules in IDDM patients and in subjects at risk for IDDM.

    Diabetes·1992
    Same author

    One pharmacist's work for AIDS patients.

    American pharmacy·1992
    Same author

    Definition of HLA class II genotypes and phenotypes for matching solid organ donors and their recipients.

    Transplantation proceedings·1992
    Same author

    Critical importance of HLA antigen matching in cadaveric kidney transplantation with high overall survival rates. The Manchester UK Kidney Transplant Team.

    Transplantation proceedings·1992

    Area of Science:

    • Dermatology
    • Genetics
    • Immunology

    Background:

    • Familial cold urticaria is a rare genetic disorder characterized by skin reactions following cold exposure.
    • Previous terminology is potentially misleading as the condition does not typically involve urticaria.

    Observation:

    • A 65-year-old patient presented with an erythematous, burning papular eruption, fever, and arthropathy post-cold exposure.
    • Affected family members exhibited an autosomal dominant inheritance pattern.
    • Histopathology revealed telangiectasia and neutrophilic perivascular inflammation.

    Findings:

    • The clinical and histopathological findings support a distinct syndrome triggered by cold.
    • The condition is inherited in an autosomal dominant manner.
    • The eruption is papular and inflammatory, not urticarial.

    Related Experiment Videos

    Implications:

    • Reclassifying the condition as "familial polymorphous cold eruption" offers a more accurate description.
    • Understanding the genetic and inflammatory pathways is crucial for potential therapeutic targets.
    • This research aids in differentiating it from other cold-induced dermatoses.