Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Right Ventricular function in aortic and mitral valve disease

G G Winzelberg, C A Boucher, G M Pohost

    Chest
    |May 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Restriction Fragment Length Polymorphism Analyses of Iranian Strains of Xanthomonas campestris from Cereals and Grasses.

    Plant disease·2019
    Same author

    Treatment of hepatitis C monoinfection in adults--Dutch national guidelines.

    The Netherlands journal of medicine·2013
    Same author

    Prediction of response to antiretroviral therapy by human experts and by the EuResist data-driven expert system (the EVE study).

    HIV medicine·2010
    Same author

    The parish pump [venereal disease control].

    Health education journal·2010
    Same author

    Oseltamivir-resistant influenza A(H1N1) viruses detected in Europe during season 2007-8 had epidemiologic and clinical characteristics similar to co-circulating susceptible A(H1N1) viruses.

    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin·2009
    Same author

    Evaluation of a rapid molecular algorithm for detection of pandemic influenza A (H1N1) 2009 virus and screening for a key oseltamivir resistance (H275Y) substitution in neuraminidase.

    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2009
    Same journal

    The effect of a two-day stay at high altitude (2500 m) on right ventricular afterload and oxygen delivery in patients with pulmonary vascular disease A randomized controlled crossover trial.

    Chest·2026
    Same journal

    A Comparative Study of Radiation Exposure in Conventional and Robotic Bronchoscopy.

    Chest·2026
    Same journal

    Independent Prognostic Contributions of Anti-Ro52 and Anti-MDA5 in Autoimmune-Associated Interstitial Lung Disease.

    Chest·2026
    Same journal

    Lung aeration and gas exchange in SGA or AGA infants with moderate-severe BPD: secondary analysis of the PATH-BPD study.

    Chest·2026
    Same journal

    Lung Cancer Incidence and Mortality after Negative Low-Dose CT Screening Results.

    Chest·2026
    Same journal

    Symptom prevalence and impact on lung cancer risk in the SUMMIT study.

    Chest·2026
    See all related articles

    Radionuclide ventriculography accurately assesses right ventricular ejection fraction (RVEF) in patients with severe aortic or mitral valve disease. Elevated right ventricular pressures significantly correlate with reduced RVEF and central venous reflux.

    Area of Science:

    • Cardiology
    • Nuclear Medicine
    • Cardiovascular Imaging

    Background:

    • Severe aortic or mitral valve disease can impact right ventricular function.
    • Assessing right ventricular function is crucial for managing valvular heart disease.

    Purpose of the Study:

    • To evaluate the utility of radionuclide ventriculography in assessing right ventricular function in patients with severe aortic or mitral valve disease.
    • To correlate right ventricular ejection fraction (RVEF) and central venous reflux with catheterization findings.

    Main Methods:

    • Gated first-pass radionuclide ventriculography was performed in 56 patients (13 controls, 43 with valvular disease).
    • Right ventricular ejection fraction (RVEF) and central venous reflux were determined.
    • Findings were related to right ventricular peak systolic pressures and filling pressures.

    Related Experiment Videos

    Main Results:

    • Reduced RVEF was observed in 55% of valvular disease patients with right ventricular peak systolic pressures > 50 mm Hg, compared to 14% with pressures < 50 mm Hg (P < .05).
    • Central venous systolic reflux was present in 88% of patients with right ventricular systolic pressures > 55 mm Hg, compared to 25% with pressures < 55 mm Hg (P < .1).
    • No correlation was found between RVEF and ventricular filling pressure in valvular heart disease patients.

    Conclusions:

    • Radionuclide assessment of right ventricular function provides valuable information not obtainable from pressure measurements alone in patients with aortic or mitral valve disease.
    • RVEF and central venous reflux are sensitive indicators of right ventricular dysfunction in the context of severe valvular heart disease.