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Antiallergic activity of some 9H-xanthen-9-one-2-carboxylic acids
Journal of Medicinal Chemistry
|December 1, 1978
Abstract:
The synthesis and antiallergic activity of a new series of 9H-xanthen-9-one-2-carboxylic acids are described. Antiallergic activity was evaluated in the rat passive cutaneous anaphylaxis (PCA) screen. Biological results were analyzed using regression analysis techniques, and the antiallergic activity of the compounds in the series was found to be highly correlated with substituent size.