[Effect of heparin in uremic patients during hemodialysis]

A sufficient level of heparin was maintained during hemodialysis by heparinization with initially 5000 I.U. and subsequently 1500 I.U./hour continuously. Active heparin amounted 70% of total heparin during the entire procedure. The elimination rate of heparin increased fivefold in patients with a decrease of the albumin-globulin ratio. The antithrombin III level was found to be slightly reduced. Levels of Hageman-factor as well as fibrinogen remained constant during the dialysis procedure.