A rapid and specific method for measuring chloramphenicol degradation in aqueous solution following autoclaving
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Abstract:
An HPLC method is reported for the measurement of chloramphenicol and its degradation product following autoclaving. The procedure, using a reversed-phase column and potassium phosphate solution as the solvent, is shown to be suitable for monitoring chloramphenicol degradation in intrathecal injections after sterilisation.
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