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Orbital infarction in sickle cell disease

J P Blank, F M Gill

    Pediatrics
    |June 1, 1981
    PubMed
    Summary

    Sickle cell disease can cause bone infarction, sometimes affecting the orbital bone. This can lead to symptoms like headache, proptosis, and eyelid swelling, mimicking infection.

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    Area of Science:

    • Hematology
    • Ophthalmology
    • Radiology

    Background:

    • Bone infarction is a known complication of sickle cell disease.
    • Orbital bone involvement can present with complex symptoms.

    Observation:

    • Three cases presented with frontal headache, proptosis, and eyelid edema.
    • These symptoms were associated with orbital bone infarction.

    Findings:

    • Radionuclide scanning aided in differentiating bone infarction from orbital infection in one patient.
    • Clinical presentation can overlap between bone infarction and orbital cellulitis.

    Implications:

    • Highlights the importance of considering bone infarction in sickle cell patients with orbital symptoms.
    • Suggests radionuclide scanning as a valuable diagnostic tool in such cases.
    • Emphasizes the need for accurate diagnosis to guide appropriate treatment strategies.