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Laparoscopic Anatomic S7+S8d Resection Preserving Inferior Right Hepatic Vein and S6 with Right Hepatic Vein Transection
Published on: December 30, 2025
[Ischemic hepatitis. Clinico-pathological presentation of 2 cases]
Insights
Congestive heart failure can lead to ischemic hepatitis, a condition also known as shock liver. This occurs due to liver perfusion failure, causing elevated liver enzymes and centrizonal necrosis.
Area of Science:
- Hepatology
- Cardiology
- Pathology
Background:
- Congestive heart failure (CHF) is a complex cardiovascular condition.
- Viral hepatitis is a common differential diagnosis for elevated liver enzymes.
Observation:
- Two female patients with CHF presented with elevated cytolytic hepatic enzymes.
- Clinical presentation suggested viral hepatitis.
Findings:
- Autopsy revealed extensive ischemic centrizonal necrosis (shock liver) in both patients.
- This pathology indicated liver perfusion failure as the cause.
Implications:
- Ischemic hepatitis should be considered in patients with CHF and elevated transaminases.
- Understanding shock liver is crucial for managing critical care patients.
Abstract:
Just before death, two female patients with congestive heart failure exhibited marked elevation of cytolytic hepatic enzymes, suggesting the diagnosis of viral hepatitis. Histologic examination of autopsy material led us to conclude in both cases on the presence of extensive and confluent ischemic centrizonal necrosis (shock liver). This picture probably reflected the consequences of liver perfusion failure. Ischemic hepatitis is the association of shock liver with marked elevation of transaminases.
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