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Some epidemiological aspects of congenital heart disease in Denmark

H B Laursen

    Acta Paediatrica Scandinavica
    |September 1, 1980
    PubMed

    Insights

    Congenital heart disease (CHD) affects 6.1% of Danish children, with ventricular septal defects most common. Lethality reaches 48% by age 15, highlighting the critical need for early diagnosis and intervention.

    Area of Science:

    • Pediatrics
    • Cardiology
    • Public Health

    Background:

    • Congenital heart disease (CHD) represents a significant global health concern affecting children.
    • Understanding the prevalence, common types, and outcomes of CHD is crucial for effective healthcare planning.

    Purpose of the Study:

    • To determine the prevalence and incidence of congenital heart disease (CHD) in Danish children.
    • To analyze the common types of CHD, age at diagnosis, and survival rates.
    • To investigate the familial occurrence of CHD.

    Main Methods:

    • A comprehensive data collection involving 5249 children aged 0-15 years from all Danish pediatric and cardiological departments.
    • Inclusion of data from death certificates to ensure complete ascertainment.
    • Analysis of prevalence, diagnostic timing, sex distribution, specific cardiac anomalies, lethality, and sibling occurrence.

    Main Results:

    • Mean CHD prevalence in Denmark was 6.1% (1963-1973), increasing to 7.0% (1972-1973).
    • Ventricular septal defect was the most frequent anomaly (24.0%), followed by persistent ductus arteriosus (12.6%).
    • Cumulative lethality was 25% at 1 month, 42% at 5 years, and 48% by age 15. CHD occurred in 2.3% of siblings.

    Conclusions:

    • Congenital heart disease (CHD) remains a significant issue in Denmark with substantial long-term lethality.
    • Early diagnosis within the first year of life is critical, though a considerable proportion are diagnosed later.
    • The findings underscore the importance of continued research and improved management strategies for pediatric cardiovascular conditions.

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