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Related Experiment Videos

Plague in a neonate

M E White, R J Rosenbaum, T M Canfield

    American Journal of Diseases of Children (1960)
    |May 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Plague is frequently diagnosed in children in the US, particularly in the western states. Early diagnosis and treatment are crucial for managing this serious bacterial infection in pediatric patients.

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    Area of Science:

    • Pediatric infectious diseases
    • Epidemiology
    • Public health

    Background:

    • Plague is a serious zoonotic disease caused by the bacterium Yersinia pestis.
    • Historically, plague outbreaks have posed significant public health challenges.
    • Understanding the epidemiology of plague in specific populations is vital for effective control.

    Observation:

    • Over half of all reported plague cases in the United States occur in children.
    • A notable increase in plague incidence was observed in the 1970s, with a 350% rise compared to the 1960s.
    • Children presenting with sepsis and lymphadenopathy in the western US should be evaluated for plague.

    Findings:

    • Plague in children can manifest with severe complications, including meningitis, metabolic encephalopathy, abscess formation, and pneumonia.

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  • Prompt and appropriate antibiotic treatment typically leads to a rapid clinical improvement.
  • Effective management requires strict isolation protocols and thorough epidemiologic investigation to prevent disease transmission.

    • Implications:

    • Pediatricians and healthcare providers in endemic areas must maintain a high index of suspicion for plague.
    • Timely diagnosis and treatment are critical to reduce morbidity and mortality in affected children.
    • Public health surveillance and control measures are essential to mitigate the impact of plague in the pediatric population.