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Related Experiment Videos

Heart block in Marfan's syndrome

S Keidar, E Grenadier, L Cohen

    Angiology
    |June 1, 1981
    PubMed
    Summary

    Marfan syndrome, a connective tissue disorder, can rarely cause heart rhythm problems. This case report details a patient with heart block and ventricular arrhythmias who received a pacemaker.

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    Area of Science:

    • Cardiology
    • Genetics
    • Connective Tissue Diseases

    Background:

    • Marfan syndrome is a heritable connective tissue disorder.
    • Classic Marfan syndrome involves ocular, aortic, and skeletal abnormalities.
    • Cardiac conduction disturbances and arrhythmias are rare in Marfan syndrome.

    Observation:

    • This case report describes a patient with symptomatic heart block.
    • The patient presented with a prolonged atrial-His interval and ventricular arrhythmia.
    • A permanent ventricular pacemaker was implanted in the patient.

    Findings:

    • Rare cardiac manifestations of Marfan syndrome include conduction disturbances and ventricular arrhythmias.
    • Symptomatic heart block and ventricular arrhythmias can occur in Marfan syndrome.
    • Pacemaker implantation is a viable treatment for severe cardiac conduction issues in Marfan syndrome.

    Implications:

    • Highlights the importance of cardiac evaluation in Marfan syndrome patients.
    • Suggests that rare cardiac complications should be considered in Marfan syndrome.
    • Demonstrates successful management of severe arrhythmias in Marfan syndrome with pacemaker implantation.

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