[Hematological features of sickle-cell disease (author's transl)]

The diagnosis of S hemoglobin is easy and always given by the laboratory. It must be performed in every black individual. Three tests are commonly used: Emmel test, in vitro solubility test and electrophoresis which, is necessary to differenciate homozygotic and heterozygotic individuals. The others blood data are liable to vary according to the homo or heterozygotic condition and to the evolutive periods of the disease. One must always consider the eventuality of an association of S hemoglobin with an another abnormal hemoglobin or with various hematological conditions.