[Behavior of hemodynamic and blood-gas parameters after intravenous salbutamol]

The haemodynamic effects of salbutamol were studied in 14 patients with chronic obstructive lung disease with a single dose of 100 and 200 gamma, administered by i.v. injection. The results of study revealed salbutamol intravenous injection significantly increases heart rate, cardiac index and decreases vascular systemic resistance. There was no significant change in blood gas tensions. This study indicates that salbutamol produces variation in preload and afterload by a direct action on vascular smooth muscle.