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Related Experiment Videos

[Creatinine in the amniotic fluid]

A Ciani, N Conte, A Turinetto

    Bollettino Della Societa Italiana Di Biologia Sperimentale
    |September 30, 1980
    PubMed
    Summary
    This summary is machine-generated.

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    Creatinine levels in amniotic fluid increase significantly after 34 weeks of pregnancy, supporting fetal urine as a source and aiding in fetal maturity assessment.

    Area of Science:

    • Obstetrics and Gynecology
    • Biochemistry
    • Perinatal Medicine

    Context:

    • Investigated creatinine concentration in amniotic fluid during the latter half of pregnancy.
    • Utilized single and serial determinations in 39 and 2 patients, respectively.

    Purpose:

    • To investigate creatinine concentration changes in amniotic fluid during late pregnancy.
    • To assess the clinical utility of creatinine levels for estimating fetal maturity.

    Summary:

    • Creatinine concentrations remained stable or increased gradually until approximately 34 weeks gestation.
    • A more abrupt increase in creatinine levels was observed after 37 weeks, reaching 1.5 mg.
    • These findings support the theory of fetal urine contributing to amniotic fluid volume.

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    Impact:

    • Provides physiological evidence for fetal urine's role in amniotic fluid production.
    • Suggests that amniotic fluid creatinine assay can be a valuable clinical tool for determining fetal maturity.
    • Contributes to understanding fetal development and perinatal health assessment.