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[Autoantibodies in advanced old-age]
Bollettino Della Societa Italiana Di Biologia Sperimentale
|January 30, 1981
Abstract:
A variety of autoantibodies (anti-nuclear, anti-mitochondrial, anti-smooth muscle, anti-gastric parietal cell) were measured by indirect immunofluorescence. At least one of such autoantibodies was detected in 65.2% of 46 old people sera (ranging from 76 to 95). Both a decrease in the efficiency of the immune response and a failure of the immunoregulatory mechanisms occurring with age may account for the above findings.