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Renal function after high dose urography in patients with renal failure
The British Journal of Radiology
|June 1, 1981
Summary
High-dose urography did not cause acute renal failure in patients with moderate to severe kidney problems. Most patients experienced no decline in kidney function after the procedure.
Area of Science:
- Nephrology
- Radiology
- Medical Imaging
Background:
- High-dose urography is an imaging technique used to visualize the urinary tract.
- Patients with moderate to severe renal failure may be at increased risk of contrast-induced nephropathy.
- Assessing the safety of high-dose urography in this patient population is crucial.
Purpose of the Study:
- To evaluate the incidence of acute renal failure following high-dose urography in patients with moderate to severe renal impairment.
- To determine if high-dose urography leads to worsening of renal function in this vulnerable group.
Main Methods:
- A retrospective study was conducted on 40 patients with moderate to severe renal failure.
- Patients underwent high-dose urography.
- Renal function was monitored post-procedure, specifically for oliguric acute renal failure and changes in serum creatinine.
Main Results:
- None of the 40 patients developed oliguric acute renal failure after high-dose urography.
- Renal function remained stable in 37 patients.
- Three patients experienced a transient rise in serum creatinine without oliguria within a week of the procedure.
- Worsening renal function was not attributed to the urogram in the majority of cases.
Conclusions:
- High-dose urography appears to be safe in patients with moderate to severe renal failure.
- The procedure is unlikely to cause oliguric acute renal failure or significant worsening of kidney function.
- Further investigation into regional differences in patient outcomes may be warranted.
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