Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Meningitis complicating transsphenoidal hypophysectomy

B Romanowski, D L Tyrrell, B K Weir

    Canadian Medical Association Journal
    |May 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effect of Vacancy Concentration on Elastic and Electronic Properties of InAs and GaAs: Towards Defected Structures of Nanoobjects.

    Journal of nanoscience and nanotechnology·2016
    Same author

    Hcmv-miR-UL22A-5p: A Biomarker in Transplantation With Broad Impact on Host Gene Expression and Potential Immunological Implications.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2015
    Same author

    The Pekin duck programmed death-ligand 1: cDNA cloning, genomic structure, molecular characterization and mRNA expression analysis.

    International journal of immunogenetics·2015
    Same author

    Safety and immunogenicity of a glycoprotein D genital herpes vaccine in healthy girls 10-17 years of age: results from a randomised, controlled, double-blind trial.

    Vaccine·2013
    Same author

    Immune responses elicited by a fourth dose of the HPV-16/18 AS04-adjuvanted vaccine in previously vaccinated adult women.

    Vaccine·2012
    Same author

    Short-course itraconazole in the treatment of candida vulvovaginitis: A multicentre Canadian study.

    The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses·2012
    Same journal

    Tularaemia; a problem in diagnosis.

    Canadian Medical Association journal·2010
    Same journal

    CONTROL of cancer.

    Canadian Medical Association journal·2010
    Same journal

    Bilateral diphtheritic external otitis treated with sulfathiazole.

    Canadian Medical Association journal·2010
    Same journal

    Hypoplastic anaemia treated with transfusions and folic acid fraction.

    Canadian Medical Association journal·2010
    Same journal

    Lauron in rheumatoid arthritis; a further report.

    Canadian Medical Association journal·2010
    Same journal

    HOW the socialist looks at national health service in England.

    Canadian Medical Association journal·2010
    See all related articles

    Postoperative cerebrospinal fluid (CSF) leaks and meningitis following transsphenoidal hypophysectomy are significant risks. Diabetes mellitus and CSF leaks are identified as key risk factors for developing meningitis after this surgery.

    Area of Science:

    • Neurosurgery
    • Infectious Disease Epidemiology

    Background:

    • Transsphenoidal hypophysectomy is a surgical procedure to remove the pituitary gland.
    • Postoperative complications, including cerebrospinal fluid (CSF) leaks and meningitis, can occur.

    Purpose of the Study:

    • To determine the incidence of cerebrospinal rhinorrhea and meningitis after transsphenoidal hypophysectomy.
    • To identify risk factors associated with meningitis following this procedure.

    Main Methods:

    • Retrospective review of 98 patient records who underwent transsphenoidal hypophysectomy between 1969 and 1979.
    • Analysis of complication rates, specifically CSF rhinorrhea and meningitis.

    Main Results:

    • Seven cases of cerebrospinal rhinorrhea and six cases of meningitis were recorded.

    Related Experiment Videos

  • Diabetes mellitus (5/6 meningitis cases) and cerebrospinal rhinorrhea (3/7 meningitis cases) were significant risk factors for meningitis (P < 0.001).
  • Two confirmed and two suspected cases of anaerobic meningitis were noted.

    • Conclusions:

    • Cerebrospinal rhinorrhea and diabetes mellitus are significant risk factors for meningitis post-transsphenoidal hypophysectomy.
    • Prophylactic antibiotics did not prevent meningitis in this patient cohort.