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Drosophila importin alpha1 performs paralog-specific functions essential for gametogenesis.

The NOTCH receptor and its ligands.

Structural conservation of Notch receptors and ligands.

A dominant-negative form of Serrate acts as a general antagonist of Notch activation.

Serrate-mediated activation of Notch is specifically blocked by the product of the gene fringe in the dorsal compartment of the Drosophila wing imaginal disc.

Beaded of Goldschmidt, an antimorphic allele of Serrate, encodes a protein lacking transmembrane and intracellular domains.

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