[IgD plasmocytoma: clinical and differential diagnostic features (author's transl)]

A 64-year-old man died of IgD plasmocytoma only two months after onset of first symptoms. The course of the disease was characterized by marked renal insufficiency, hypercalcaemia with cardiac arrhythmias and bone destruction, in addition to raised phosphate concentration and alkaline phosphatase activity. The electrophoresis diagram was unremarkable and had no M-peak. But immunoelectrophoretic analysis of serum demonstrated a IgD paraprotein; in addition there was a monoclonal light chain, type lambda. At post-mortem the diagnosis of plasmocytoma was made; in addition there was renal amyloidosis.