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Pityriasis rosea. Viral complement fixation studies

L D Hudson, S Adelman, C W Lewis

    Journal of the American Academy of Dermatology
    |May 1, 1981
    PubMed
    Summary
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    This study investigated pityriasis rosea patients for viral or Mycoplasma infections. Complement fixation tests showed no significant viral or Mycoplasma titers, suggesting these common pathogens are unlikely causes.

    Area of Science:

    • Dermatology
    • Virology
    • Microbiology

    Background:

    • Pityriasis rosea is a common skin condition of unknown etiology.
    • Previous research has explored potential infectious triggers for pityriasis rosea.

    Purpose of the Study:

    • To investigate the role of common respiratory viruses and Mycoplasma in the etiology of pityriasis rosea.
    • To determine if serological evidence of infection correlates with pityriasis rosea presentation.

    Main Methods:

    • Eleven patients diagnosed with pityriasis rosea were enrolled.
    • Acute and convalescent serum samples were collected from patients.
    • Complement fixation tests were performed to detect antibodies against various respiratory viruses and Mycoplasma pneumoniae.

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    Main Results:

    • A history of antecedent upper respiratory illness was reported by 6 out of 11 patients.
    • No significant rise in antibody titers was detected in any patient for the tested viruses or Mycoplasma.
    • Complement fixation test results did not reveal a serological link between common respiratory pathogens and pityriasis rosea.

    Conclusions:

    • The study found no significant serological evidence supporting a causal role for the investigated respiratory viruses or Mycoplasma in pityriasis rosea.
    • Further research is needed to elucidate the specific etiology of pityriasis rosea.