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Peritoneal dialysis during peritonitis

J Rubin, S McFarland, E W Hellems

    Kidney International
    |March 1, 1981
    PubMed
    Summary
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    Peritonitis significantly impacts peritoneal dialysis, reducing fluid drainage and increasing solute/protein loss. These changes suggest alterations in the peritoneal membrane

    Area of Science:

    • Nephrology
    • Renal Replacement Therapy
    • Peritoneal Dialysis Complications

    Background:

    • Peritonitis is the most common complication of peritoneal dialysis.
    • Understanding peritonitis's effects on dialysis efficiency is crucial.

    Purpose of the Study:

    • To investigate the physiological changes in patients undergoing peritoneal dialysis during peritonitis episodes.
    • To identify how peritonitis affects key dialysis parameters.

    Main Methods:

    • Comparison of peritoneal dialysis patients during infection-free periods versus during clinical peritonitis.
    • Measurement of dialysate effluent volume, glucose absorption, solute clearance (urea, creatinine), and protein loss.

    Main Results:

    Related Experiment Videos

  • Peritonitis was linked to decreased dialysate effluent volume.
  • Increased absorption of glucose and enhanced clearance of urea and creatinine were observed during peritonitis.
  • Significant protein loss into the dialysate effluent occurred during peritonitis.

    • Conclusions:

    • Peritonitis alters the peritoneal dialysis membrane's function.
    • Changes in peritoneal blood flow, membrane surface area, or permeability may explain peritonitis-induced alterations.