[Testosterone-1 alpha, 2 alpha-3H(n) absorption by target organ tissues in rabbit embryos in vitro]

The dynamics of uptake of testosterone-1alpha,2alpha-3H(n) by different tissues of the reproductive system in the rabbit embryos from the 18th till 25th days of development was studied in vitro experiments. The specific uptake of the hormone was recorded at all stages under study and in all organ rudiments. The selective uptake was observed in males in the genital tubercle from the 20th till the 25th day, in the ducts on the 19--21st and 25th days, in the urogenital sinus (the cyclic one) on the 19th, 21st, 23rd and 25th days. The character of the hormone selective uptake in the organs-targets is similar in the embryos of both sexes and corresponds to the male morphogenesis. The females were, however, characterized by the higher uptake of the hormone in the ducts on the 19--21st days and in the urogenital sinus on the 19--23rd days. The hormone uptake in the gonads is similar in embryos of both the sexes. The problem of reception of the organs-targets rudiments during the period of growth and differentiation of the embryonic genital system is discussed.